Dataset Information

Risk of lead exposure from wild game consumption from cross-sectional studies in Madre de Dios, Peru.

ABSTRACT:

Background

Studies have shown elevated blood lead levels (BLL) in residents of remote communities in the Amazon, yet sources of lead exposure are not fully understood, such as lead ammunition consumed in wild game.

Methods

Data was collected during two cross-sectional studies that enrolled 307 individuals in 26 communities. Regression models with community random effects were used to evaluate risk factors for BLLs, including diet, water source, smoking, sex, age, and indigenous status. The All-Ages Lead Model (AALM) from the Environmental Protection Agency (EPA) was used to estimate background and dose from wild game consumption.

Findings

Indigenous status and wild game consumption were associated with increased BLLs. Indigenous participants had 2.52 μg/dL (95% CI: 1.95-3.24) higher BLLs compared to non-indigenous. Eating wild game was associated with a 1.41 μg/dL (95% CI: 1.20-1.70) increase in BLLs. Two or more portions per serving were associated with increased BLLs of 1.66 μg/dL (95% CI: 1.10-2.57), compared to smaller servings. Using the AALM, we estimate background lead exposures to be 20 μg/day with consumption of wild game contributing 500 μg/meal. Lastly, we found a strong association between BLLs and mercury exposure.

Interpretation

Consumption of wild game hunted with lead ammunition may pose a common source of lead exposure in the Amazon. Communities that rely on wild game and wild fish may face a dual burden of exposure to lead and mercury, respectively.

SUBMITTER: Berky AJ

PROVIDER: S-EPMC9555248 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Risk of lead exposure from wild game consumption from cross-sectional studies in Madre de Dios, Peru.

Berky Axel J AJ Robie Emily E Navio Chipa Susy S Ortiz Ernesto J EJ Palmer Emma J EJ Rivera Nelson A NA Maria Morales Avalos Ana A Meyer Joel N JN Hsu-Kim Heileen H Pan William K WK

Lancet regional health. Americas 20220508

<h4>Background</h4>Studies have shown elevated blood lead levels (BLL) in residents of remote communities in the Amazon, yet sources of lead exposure are not fully understood, such as lead ammunition consumed in wild game.<h4>Methods</h4>Data was collected during two cross-sectional studies that enrolled 307 individuals in 26 communities. Regression models with community random effects were used to evaluate risk factors for BLLs, including diet, water source, smoking, sex, age, and indigenous st ...[more]

PMID: 36237535

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Dataset Information

Risk of lead exposure from wild game consumption from cross-sectional studies in Madre de Dios, Peru.

Background

Methods

Findings

Interpretation

Publications

Risk of lead exposure from wild game consumption from cross-sectional studies in Madre de Dios, Peru.

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