Ontology highlight
ABSTRACT:
SUBMITTER: Concina G
PROVIDER: S-EPMC9555644 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Concina Giulia G Renna Annamaria A Milano Luisella L Sacchetti Benedetto B
PLoS biology 20220930 9
Long-term memory formation involves the reorganization of brain circuits, termed system consolidation. Whether and how a prior fear experience influences system consolidation of new memories is poorly understood. In rats, we found that prior auditory fear learning allows the secondary auditory cortex to immediately encode new auditory memories, with these new memories purely requiring the activation of cellular mechanisms of synaptic consolidation within secondary auditory cortex. Similar result ...[more]