An Innovative Approach to Building an Effective and Efficient Pediatric Trial Network.
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ABSTRACT:
SUBMITTER: Randell RL
PROVIDER: S-EPMC9558054 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Publications
An Innovative Approach to Building an Effective and Efficient Pediatric Trial Network.
Randell Rachel L RL Benjamin Daniel K DK Greenberg Rachel G RG
Hospital pediatrics 20220901 9
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Project description:BackgroundCost is a barrier to creating educational resources, and new educational initiatives are often limited in distribution. Medical training programs must develop strategies to create and implement cost-effective educational programming.ObjectiveWe developed high-quality medical programming in procedural instruction with efficient economics, reaching the most trainees at the lowest cost.MethodsThe Just-In-Time online procedural program was developed at the University of Toronto in Canada, aiming to teach thoracentesis, paracentesis, and lumbar puncture skills to internal medicine trainees. Commercial vendors quoted between CAD $50,000 and $100,000 to create 3 comprehensive e-learning procedural modules-a cost that was prohibitive. Modules were therefore developed internally, utilizing 4 principles aimed at decreasing costs while creating efficiencies: targeting talent, finding value abroad, open source expansion, and extrapolating efficiency.ResultsProcedural modules for thoracentesis, paracentesis, and lumbar puncture were created for a total cost of CAD $1,200, less than 3% of the anticipated cost in utilizing traditional commercial vendors. From November 2016 until October 2018, 1800 online instructional sessions have occurred, with over 3600 pageviews of content utilized. While half of the instructional sessions occurred within the city of Toronto, utilization was documented in 10 other cities across Canada.ConclusionsThe Just-in-Time online instructional program successfully created 3 procedural modules at a fraction of the anticipated cost and appeared acceptable to residents based on website utilization.
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Project description:BackgroundCapacity-building initiatives targeting medical personnel in low- and middle-income countries have focused on individual medical professionals within specific disciplines. However, it has become evident that the enhancement of healthcare quality necessitates more than just individual capacity-building efforts. As a part of The National Radiotherapy and Medical Oncology Center Project in Côte d'Ivoire, the National Cancer Center Korea has initiated a training project for hospital personnel in Côte d'Ivoire.MethodsFrom May to November 2023, 51 hospital personnel from 21 disciplines from Côte d'Ivoire underwent invitation-based training in Korea. A quantitative analysis of the training outcomes for the trainees and a qualitative assessment of the enablers of the training, involving trainees, trainers, and the coordinating team, were conducted.ResultsThe average score at pre- and post-training evaluation of capabilities of the trainees increased from 2.3 to 4.0 (out of 5.0). In addition to medical knowledge and technical skills sharing, trainees collaborated in group activities to develop workflow manuals for disease-, discipline-, and department-specific tasks through a multidisciplinary and cross-functional approach. The qualitative assessment indicated the importance of contextually relevant curriculum development with a special focus on establishing hospital operational plans, maintaining trainee autonomy and motivation, building mutual trust and cooperation between partner countries, engaging stakeholders actively, and providing effective leadership and support structures through a dedicated coordinating team were crucial factors for program success.ConclusionsEffective hospital personnel capacity building programs should not only focus on imparting medical knowledge and technical skills but also actively engage trainees in developing hospital operational plans. Furthermore, ensuring mutual trust and cooperation among various stakeholders, along with the establishment of a dedicated coordinating team, is essential for the success of the program.
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Project description:BackgroundIn some current healthcare settings, there is a noticeable absence of national institutions committed to the synthesis and use of evidence in healthcare decision- and policy-making. This absence creates a need to broaden the responsibilities of healthcare providers to include knowledge brokering and advocacy in order to optimize knowledge translation to other stakeholders, especially policy-makers. However, this process requires practitioners and researchers to acquire certain types of knowledge and skills. This article introduces two innovative methods for capacity building in knowledge translation (KT).MethodsDuring a workshop aimed at preparing 21 trainers in evidence-based medicine, two innovative methods were used: (1) debate and (2) a knowledge translation project (KTP). The main objective of the debates approach was to strengthen participants' critical thinking abilities by requiring them to search for and appraise evidence and defend their arguments. The KTP was used to introduce participants to the essential steps of knowledge translation and to suggest an extended role for healthcare practitioners, i.e., using evidence to manage not only individual patients but also to a community of patients. Participants' performances were assessed according to a pre-designed scheme. At the end of the workshop, participants' opinions and experiences with the innovative teaching methods were evaluated based on their answers to a questionnaire and the results of small-group discussions.ResultsThe participants performed well in both the debate and KTP methods. During post-workshop group discussions, they indicated that the debate approach had added a new dimension to their evidence-based medicine skills by adding purpose and motivation. However, they felt that their performances would have been better if they had been offered practical demonstrations of how to conduct the debate. The participants indicated that the KTP enhanced their understanding of the relationships between evidence and implementation, and motivated them to investigate public health problems in addition to individual patient problems. However, some participants maintained that these issues fell outside the scope of their role as doctors.ConclusionDebates and evidence implementation through KTP are generally well accepted by healthcare practitioners as methods by which they can improve their skills in KT.
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Project description:In China, the focus of drug research and development has gradually shifted from generic to innovative drugs. Using the Chinese Clinical Trials Registry and Information Transparency Platform, we retrospectively analyzed clinical trials of innovative pediatric drugs conducted in mainland China over the last decade. The goal of this work was to better understand the characteristics of and historical changes in innovative pediatric drug research and development (R&D) in China and to provide effective data support for policy makers and other stakeholders. This study included 198 innovative pediatric drug clinical trials. The data showed that, although some progress has been made in the R&D of innovative pediatric drugs in China, many factors limiting this progress still exist, such as concentrated R&D areas, inadequate pediatric participants, and unbalanced source distributions. The level of innovative pediatric drug R&D in China currently lags behind the global level and has not kept pace with anti-neoplastic drug R&D in China. To promote the innovative development of pediatric drugs in China, the Chinese government must develop an R&D supervision framework, improve the motivation and innovation capabilities of pharmaceutical companies, and optimize the source distribution between regions.
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