Ontology highlight
ABSTRACT:
SUBMITTER: Tsai CH
PROVIDER: S-EPMC9562869 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Tsai Chia-Hung CH Weng Jing-Ru JR Lin Hsiang-Wen HW Lu Meng-Tien MT Liu Yu-Chi YC Chu Po-Chen PC Chu Po-Chen PC
Cancers 20221007 19
Triple negative breast cancer (TNBC) is considered the most aggressive breast cancer with high relapse rates and poor prognosis. Although great advances in the development of cancer therapy have been witnessed over the past decade, the treatment options for TNBC remain limited. In this study, we investigated the effect and potential underlying mechanism of the Hsp70 inhibitors, compound 1 and compound 6, on breast cancer stem cells (BCSCs) in TNBC cells. Our results showed that compound 1 and 6 ...[more]