Does the Gut Microbial Metabolome Really Matter? The Connection between GUT Metabolome and Neurological Disorders.
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SUBMITTER: Marc MA
PROVIDER: S-EPMC9571089 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
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Does the Gut Microbial Metabolome Really Matter? The Connection between GUT Metabolome and Neurological Disorders.
Marć Małgorzata Anna MA Jastrząb Rafał R Mytych Jennifer J
Nutrients 20220924 19
Herein we gathered updated knowledge regarding the alterations of gut microbiota (dysbiosis) and its correlation with human neurodegenerative and brain-related diseases, e.g., Alzheimer's and Parkinson's. This review underlines the importance of gut-derived metabolites and gut metabolic status as the main players in gut-brain crosstalk and their implications on the severity of neural conditions. Scientific evidence indicates that the administration of probiotic bacteria exerts beneficial and pro ...[more]
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