Druggable targets and therapeutic development for COVID-19.
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ABSTRACT:
SUBMITTER: Duan X
PROVIDER: S-EPMC9581228 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Druggable targets and therapeutic development for COVID-19.
Duan Xiaohua X Lacko Lauretta A LA Chen Shuibing S
Frontiers in chemistry 20221005
Coronavirus disease (COVID-19), which is caused by SARS-CoV-2, is the biggest challenge to the global public health and economy in recent years. Until now, only limited therapeutic regimens have been available for COVID-19 patients, sparking unprecedented efforts to study coronavirus biology. The genome of SARS-CoV-2 encodes 16 non-structural, four structural, and nine accessory proteins, which mediate the viral life cycle, including viral entry, RNA replication and transcription, virion assembl ...[more]
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