Ontology highlight
ABSTRACT: Background
Ambient fine particulate matter (PM2.5) adversely affects human health and has been linked to a variety of skin disorders. However, little is known about the effects of PM2.5 on psoriasis.Methods
The Beijing Medical Claim Data for Employees database recorded 500,266 outpatient visits for psoriasis during 2010-2017. A generalized additive quasi-Poisson model was used to examine the relationship between daily PM2.5 concentrations and outpatient visits for psoriasis with stratification by sex, age, and season.Results
Short-term exposure to PM2.5 was associated with outpatient visits for psoriasis-related health concerns. A same-day increase of 10 μg/m3 in PM2.5 concentrations was associated with a 0.29% (95% confidence interval: 0.26-0.32%) increase in daily outpatient visits for psoriasis. Female and older patients appeared to be more sensitive to the effects of PM2.5 (P < 0.05).Conclusions
Short-term elevations in PM2.5 concentrations may be associated with exacerbations in psoriasis. Further work is warranted to confirm the findings and elucidate the underlying biological mechanisms.
SUBMITTER: Wu J
PROVIDER: S-EPMC9597881 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Wu Junhui J Chen Hongbo H Yang Ruotong R Yu Huan H Shang Shaomei S Hu Yonghua Y
Frontiers in public health 20221013
<h4>Background</h4>Ambient fine particulate matter (PM<sub>2.5</sub>) adversely affects human health and has been linked to a variety of skin disorders. However, little is known about the effects of PM<sub>2.5</sub> on psoriasis.<h4>Methods</h4>The Beijing Medical Claim Data for Employees database recorded 500,266 outpatient visits for psoriasis during 2010-2017. A generalized additive quasi-Poisson model was used to examine the relationship between daily PM<sub>2.5</sub> concentrations and outp ...[more]