Dataset Information

Post-acute health care burden after SARS-CoV-2 infection: a retrospective cohort study.

ABSTRACT:

Background

The post-acute burden of health care use after SARS-CoV-2 infection is unknown. We sought to quantify the post-acute burden of health care use after SARS-CoV-2 infection among community-dwelling adults in Ontario by comparing those with positive and negative polymerase chain reaction (PCR) test results for SARS-CoV-2 infection.

Methods

We conducted a retrospective cohort study involving community-dwelling adults in Ontario who had a PCR test between Jan. 1, 2020, and Mar. 31, 2021. Follow-up began 56 days after PCR testing. We matched people 1:1 on a comprehensive propensity score. We compared per-person-year rates for health care encounters at the mean and 99th percentiles, and compared counts using negative binomial models, stratified by sex.

Results

Among 531 702 matched people, mean age was 44 (standard deviation [SD] 17) years and 51% were female. Females who tested positive for SARS-CoV-2 had a mean of 1.98 (95% CI 1.63 to 2.29) more health care encounters overall per-person-year than those who had a negative test result, with 0.31 (95% CI 0.05 to 0.56) more home care encounters to 0.81 (95% CI 0.69 to 0.93) more long-term care days. At the 99th percentile per-person-year, females who tested positive had 6.48 more days of hospital admission and 28.37 more home care encounters. Males who tested positive for SARS-CoV-2 had 0.66 (95% CI 0.34 to 0.99) more overall health care encounters per-person-year than those who tested negative, with 0.14 (95% CI 0.06 to 0.21) more outpatient encounters and 0.48 (95% CI 0.36 to 0.60) long-term care days, and 0.43 (95% CI -0.67 to -0.21) fewer home care encounters. At the 99th percentile, they had 8.69 more days in hospital per-person-year, with fewer home care (-27.31) and outpatient (-0.87) encounters.

Interpretation

We found significantly higher rates of health care use after a positive SARS-CoV-2 PCR test in an analysis that matched test-positive with test-negative people. Stakeholders can use these findings to prepare for health care demand associated with post-COVID-19 condition (long COVID).

SUBMITTER: McNaughton CD

PROVIDER: S-EPMC9616149 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

Post-acute health care burden after SARS-CoV-2 infection: a retrospective cohort study.

McNaughton Candace D CD Austin Peter C PC Sivaswamy Atul A Fang Jiming J Abdel-Qadir Husam H Daneman Nick N Udell Jacob A JA Wodchis Walter P WP Mostarac Ivona I Lee Douglas S DS Atzema Clare L CL

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20221001 40

<h4>Background</h4>The post-acute burden of health care use after SARS-CoV-2 infection is unknown. We sought to quantify the post-acute burden of health care use after SARS-CoV-2 infection among community-dwelling adults in Ontario by comparing those with positive and negative polymerase chain reaction (PCR) test results for SARS-CoV-2 infection.<h4>Methods</h4>We conducted a retrospective cohort study involving community-dwelling adults in Ontario who had a PCR test between Jan. 1, 2020, and Ma ...[more]

PMID: 36252983

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Dataset Information

Post-acute health care burden after SARS-CoV-2 infection: a retrospective cohort study.

Background

Methods

Results

Interpretation

Publications

Post-acute health care burden after SARS-CoV-2 infection: a retrospective cohort study.

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