Ontology highlight
ABSTRACT:
SUBMITTER: Al-Warhi T
PROVIDER: S-EPMC9635468 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Al-Warhi Tarfah T Al-Karmalawy Ahmed A AA Elmaaty Ayman Abo AA Alshubramy Maha A MA Abdel-Motaal Marwa M Majrashi Taghreed A TA Asem Medhat M Nabil Ahmed A Eldehna Wagdy M WM Sharaky Marwa M
Journal of enzyme inhibition and medicinal chemistry 20231201 1
Herein, a set of pyridine and pyrimidine derivatives were assessed for their impact on the cell cycle and apoptosis. Human breast cancer (MCF7), hepatocellular carcinoma (HEPG2), larynx cancer (HEP2), lung cancer (H460), colon cancers (HCT116 and Caco2), and hypopharyngeal cancer (FADU), and normal Vero cell lines were used. Compounds <b>8</b> and <b>14</b> displayed outstanding effects on the investigated cell lines and were further tested for their antioxidant activity in MCF7, H460, FADU, HEP ...[more]