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Medical Treatment of Pediatric Low-Grade Glioma.

ABSTRACT: Low-grade glioma (LGG) is the most common brain tumor in children and has excellent long-term survival. With an excellent survival rate, the choice of treatment involves careful consideration of minimizing late toxicity from surgery, radiation, and chemotherapy. Surgery, radiation therapy, and chemotherapy can be used as monotherapy or in combination, providing different therapeutic ratios and complications. As a result, establishing the selection of ideal therapies has been a controversial area, presenting challenges. Recent advances in understanding molecular characteristics of pediatric LGG affect classification and treatment approaches. This review aims to overview recent developments in medical treatment in pediatric LGG.

SUBMITTER: Lim YJ

PROVIDER: S-EPMC9650116 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Medical Treatment of Pediatric Low-Grade Glioma.

Lim Yeon Jung YJ

Brain tumor research and treatment 20221001 4

Low-grade glioma (LGG) is the most common brain tumor in children and has excellent long-term survival. With an excellent survival rate, the choice of treatment involves careful consideration of minimizing late toxicity from surgery, radiation, and chemotherapy. Surgery, radiation therapy, and chemotherapy can be used as monotherapy or in combination, providing different therapeutic ratios and complications. As a result, establishing the selection of ideal therapies has been a controversial area ...[more]

PMID: 36347636

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Project description: Not available

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