Differentially expressed long noncoding RNAs and mRNAs in PC12 cells under lysophosphatidylcholine stimulation.
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ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC9652419 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
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Differentially expressed long noncoding RNAs and mRNAs in PC12 cells under lysophosphatidylcholine stimulation.
Zhang Wen W Dun Su S Ping Yin Y Wang Qingliang Q Tana Siqin S Tana Aodong A Qin Si S Bao Xilinqiqige X Qimuge Alateng A Baiyin Tegexi T Yang Dezhi D Bao Siqin S Baoyin Seyin S Qimuge Wuhan W
Scientific reports 20221111 1
Lysophosphatidylcholine (LPC) was previously found to show neuroprotective effect on nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) induced signalings. Also, numerous studies reported the emerging roles of long noncoding RNAs (LncRNAs) involved in neurodegenerative disease. However, the biological mechanism of LPC and expression profile of lncRNAs has not been reported. Here, lncRNAs in PC12 cells under LPC and NGF treatment were analyzed using high throughput sequencing ...[more]
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