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Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside.

ABSTRACT: In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the disease posed a huge challenge globally. The efforts of health systems have been focused on repurposing existing drugs or developing innovative therapies to reduce the morbidity and mortality associated with SARS-CoV-2. In addition, most of the large pharmaceutical companies are intensely working on vaccine development to swiftly deliver safe and effective vaccines to prevent further spread of the virus. In this review, we will discuss the latest data on therapeutic strategies undergoing clinical trials. Additionally, we will provide a summary of vaccines currently under development.

SUBMITTER: Abadi B

PROVIDER: S-EPMC9652495 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside.

Abadi Banafshe B Aarabi Jeshvaghani Amir Hossein AH Fathalipour Hadis H Dehghan Leili L Rahimi Sirjani Kosar K Forootanfar Hamid H

Iranian journal of medical sciences 20221101 6

In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the disease posed a huge challenge globally. The efforts of health systems have been focused on repurposing existing drugs or developing innovative therapies to reduce the morbidity and mortality associat ...[more]

PMID: 36380976

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