First Isolation of Vancomycin-Resistant Enterococcus faecium Carrying Plasmid-Borne vanD1.
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ABSTRACT:
SUBMITTER: Hisatsune J
PROVIDER: S-EPMC9664843 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
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First Isolation of Vancomycin-Resistant Enterococcus faecium Carrying Plasmid-Borne <i>vanD1</i>.
Hisatsune Junzo J Tanimoto Koichi K Kohara Tadahiro T Myoken Yoshinari Y Tomita Yoshiharu Y Sugai Motoyuki M
Antimicrobial agents and chemotherapy 20221012 11
Vancomycin-resistant Enterococcus faecium carrying the <i>vanD1</i> gene on plasmid pEF-D was isolated from a fecal sample of a hospitalized patient in Japan. The strain JH5687 showed moderate resistance to vancomycin (MIC, 16 μg/mL) but remained susceptible to teicoplanin (MIC, 1 μg/mL). The backbone gene organization of pEF-D was highly homologous to that of conjugative plasmid pMG1 or pHTβ. The calculated conjugation frequency of JH5687 was 10<sup>-4</sup> to 10<sup>-5</sup> per donor cell. ...[more]
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