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Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.


ABSTRACT: Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.

SUBMITTER: Spealman P 

PROVIDER: S-EPMC9670979 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.

Spealman Pieter P   Avecilla Grace G   Matthews Julia J   Suresh Ina I   Gresham David D  

Microbiology resource announcements 20221027 11


Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor. ...[more]

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