Risk of Cardiovascular Diseases Associated With Medications Used in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Use of attention-deficit/hyperactivity disorder (ADHD) medications has increased substantially over the past decades, but there are concerns regarding their cardiovascular safety.

Objective

To provide an updated synthesis of evidence on whether ADHD medications are associated with the risk of a broad range of cardiovascular diseases (CVDs).

Data sources

PubMed, Embase, PsycINFO, and Web of Science up to May 1, 2022.

Study selection

Observational studies investigating the association between ADHD medications (including stimulants and nonstimulants) and risk of CVD.

Data extraction and synthesis

Independent reviewers extracted data and assessed study quality using the Good Research for Comparative Effectiveness (GRACE) checklist. Data were poole

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9685490 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature