Dataset Information

TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson's disease.

ABSTRACT:

Background

People with Parkinson's disease (PD) have a high fall rate and many falls are associated with turns. Despite this, there is minimal research on effects of rehabilitation on the quality of turns. Further, quantifying turns in the home may have broader implications since rehabilitation of turns would ideally improve turning in real world mobility.

Methods

Sixty people with PD and a history of falls will be randomized to receive either a novel TURNing InTervention (TURN-IT) or no intervention (control group). The TURN-IT group will be seen for 6 weeks (18 visits) for an individualized, progressive program that is based on the specific constraints of turning in PD. Wearable sensors will be used to measure 7 days of mobility, including turns, before and after intervention or control period. In addition, blinded assessments of gait, mobility and turns will occur before and after intervention for both groups and falls will be monitored for twelve months post intervention with bimonthly email questionnaires.

Discussion

This study has the potential to change how we rehabilitate and assess turning in people with PD and falls. There are several novel aspects to our study including a comprehensive turning-focused intervention that is tailored to the underlying constraints that impair turning in people with PD. Further, our outcome measure of turning quality during 7 days of daily life is novel and has implications for determining real-life changes after rehabilitation. The ultimate goal of this rehabilitation intervention is to improve how patients turn in daily life and to reduce falls.

Trials registration

This protocol is registered at clinicaltrials.gov; #NCT04897256; https://clinicaltrials.gov/ct2/show/NCT04897256?term=Horak&cond=Parkinson+Disease&draw=2&rank=4 .

SUBMITTER: King LA

PROVIDER: S-EPMC9703770 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson's disease.

King L A LA Carlson-Kuhta P P Wilhelm J L JL Lapidus J A JA Dale M L ML Talman L S LS Barlow N N Mancini M M Horak F B FB

BMC neurology 20221128 1

<h4>Background</h4>People with Parkinson's disease (PD) have a high fall rate and many falls are associated with turns. Despite this, there is minimal research on effects of rehabilitation on the quality of turns. Further, quantifying turns in the home may have broader implications since rehabilitation of turns would ideally improve turning in real world mobility.<h4>Methods</h4>Sixty people with PD and a history of falls will be randomized to receive either a novel TURNing InTervention (TURN-IT ...[more]

PMID: 36443737

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Dataset Information

TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson's disease.

Background

Methods

Discussion

Trials registration

Publications

TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson's disease.

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