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Electrochemical Detection of Dopamine using a Phenyl Carboxylic Acid-Functionalized Electrode Made by Electrochemical Reduction of a Diazonium Salt.

ABSTRACT: A glassy carbon electrode (GCE) has been modified by an in situ electrochemical reduction of an aryldiazonium salt generated from the reaction of 4-aminobenzoic acid and sodium nitrite in acidic ethanolic solution. The as-prepared phenyl carboxylic acid-modified glassy carbon electrode has been, for the first time, used for the electrochemical determination of dopamine. Under optimal experimental parameters, outstanding electrocatalytic activity, high sensitivity at a LOD of 5.6×10^-9 m, and broad linearity of 0.1 to 1000 μm were obtained. The crafted electrochemical platform demonstrated excellent stability, specificity, and anti-interference capability towards the sensing of dopamine.

SUBMITTER: Anjum S

PROVIDER: S-EPMC9728485 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Electrochemical Detection of Dopamine using a Phenyl Carboxylic Acid-Functionalized Electrode Made by Electrochemical Reduction of a Diazonium Salt.

Anjum Saima S Lou Baohua B Tahir Amiza A Aziz-Ur-Rehman Rehan H Shah Gilani M M Xu Guobao G

ChemistryOpen 20221201 12

A glassy carbon electrode (GCE) has been modified by an in situ electrochemical reduction of an aryldiazonium salt generated from the reaction of 4-aminobenzoic acid and sodium nitrite in acidic ethanolic solution. The as-prepared phenyl carboxylic acid-modified glassy carbon electrode has been, for the first time, used for the electrochemical determination of dopamine. Under optimal experimental parameters, outstanding electrocatalytic activity, high sensitivity at a LOD of 5.6×10<sup>-9</sup> ...[more]

PMID: 36478448

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