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Inducing a mental context for associative memory formation with real-time fMRI neurofeedback.


ABSTRACT: Memory, one of the hallmarks of human cognition, can be modified when humans voluntarily modulate neural population activity using neurofeedback. However, it is currently unknown whether neurofeedback can influence the integration of memories, and whether memory is facilitated or impaired after such neural perturbation. In this study, participants memorized objects while we provided them with abstract neurofeedback based on their brain activity patterns in the ventral visual stream. This neurofeedback created an implicit face or house context in the brain while memorizing the objects. The results revealed that participants created associations between each memorized object and its implicit context solely due to the neurofeedback manipulation. Our findings shed light onto how memory formation can be influenced by synthetic memory tags with neurofeedback and advance our understanding of mnemonic processing.

SUBMITTER: Collin SHP 

PROVIDER: S-EPMC9731952 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Inducing a mental context for associative memory formation with real-time fMRI neurofeedback.

Collin Silvy H P SHP   van den Broek Philip L C PLC   van Mourik Tim T   Desain Peter P   Doeller Christian F CF  

Scientific reports 20221208 1


Memory, one of the hallmarks of human cognition, can be modified when humans voluntarily modulate neural population activity using neurofeedback. However, it is currently unknown whether neurofeedback can influence the integration of memories, and whether memory is facilitated or impaired after such neural perturbation. In this study, participants memorized objects while we provided them with abstract neurofeedback based on their brain activity patterns in the ventral visual stream. This neurofe  ...[more]

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