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A Hybrid MCDM Approach Based on Fuzzy-Logic and DEMATEL to Evaluate Adult Obesity.

ABSTRACT: Obesity and its complications is one of the main issues in today's world and is increasing rapidly. A wide range of non-contagious diseases, for instance, diabetes type 2, cardiovascular, high blood pressure and stroke, numerous types of cancer, and mental health issues are formed following obesity. According to the WHO, Malaysia is the sixth Asian country with an adult population suffering from obesity. Therefore, identifying risk factors associated with obesity among Malaysian adults is necessary. For this purpose, this study strives to investigate and assess the risk factors related to obesity and overweight in this country. A quantitative approach was employed by surveying 26 healthcare professionals by questionnaire. Collected data were analyzed with the DEMATEL and Fuzzy Rule-Based methods. We found that lack of physical activity, insufficient sleep, unhealthy diet, genetics, and perceived stress were the most significant risk factors for obesity.

SUBMITTER: Safaei M

PROVIDER: S-EPMC9740807 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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A Hybrid MCDM Approach Based on Fuzzy-Logic and DEMATEL to Evaluate Adult Obesity.

Safaei Mahmood M A Sundararajan Elankovan E Asadi Shahla S Nilashi Mehrbakhsh M Ab Aziz Mohd Juzaiddin MJ Saravanan M S MS Abdelhaq Maha M Alsaqour Raed R

International journal of environmental research and public health 20221122 23

Obesity and its complications is one of the main issues in today's world and is increasing rapidly. A wide range of non-contagious diseases, for instance, diabetes type 2, cardiovascular, high blood pressure and stroke, numerous types of cancer, and mental health issues are formed following obesity. According to the WHO, Malaysia is the sixth Asian country with an adult population suffering from obesity. Therefore, identifying risk factors associated with obesity among Malaysian adults is necess ...[more]

PMID: 36497509

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Project description:In response to challenges from the COVID-19 pandemic and climate change to achieve the goal of ensuring sustainable economic growth, offshore wind power development not only provides a clean and sustainable source of energy but also provides opportunities for economic growth and job creation. Offshore wind energy projects have been promptly suggested in Vietnam due to policy advancement, with the country's excellent wind resources. The success of an offshore wind energy project is decided mainly by choosing the best location for offshore wind power station (OWPS) construction, which is a complex multicriteria decision-making (MCDM) problem with the coexistence of conflicting factors. There is a problem with incomplete decision information use and information loss during the decision-making process, and it is easy to overlook the interaction difficulty in a fuzzy environment. To address the complex nature of the prioritization problem posed, this study proposes a hybrid MCDM framework combining the spherical fuzzy analytical hierarchy process (SF-AHP) and weighted aggregated sum product assessment (WASPAS). SF-AHP is used in the first stage to determine the significance levels of OWPS evaluation criteria. WASPAS is then utilized to rank locations of OWPS. A comprehensive set of evaluation criteria developed based on the concept of sustainable development has been recognized by reviewing the literature review and interviewing experts to practice the two-stage MCDM model. A real case study for Vietnam is conducted to test the effectiveness of the proposed method. The best location schemes have been determined by using the decision framework. The results of the sensitivity analysis and a comparison analysis demonstrate that the decision framework is practical and robust. The proposed methodology can be used to attain a decision-making process at the regional level for offshore wind farm planning and coastal development, and the study results encourage the establishment of renewable energy development policies.

Project description:BackgroundTo date, only a limited number of transcriptional regulatory interactions have been uncovered. In a pilot study integrating sequence data with microarray data, a position weight matrix (PWM) performed poorly in inferring transcriptional interactions (TIs), which represent physical interactions between transcription factors (TF) and upstream sequences of target genes. Inferring a TI means that the promoter sequence of a target is inferred to match the consensus sequence motifs of a potential TF, and their interaction type such as AT or RT is also predicted. Thus, a robust PWM (rPWM) was developed to search for consensus sequence motifs. In addition to rPWM, one feature extracted from ChIP-chip data was incorporated to identify potential TIs under specific conditions. An interaction type classifier was assembled to predict activation/repression of potential TIs using microarray data. This approach, combining an adaptive (learning) fuzzy inference system and an interaction type classifier to predict transcriptional regulatory networks, was named AdaFuzzy.ResultsAdaFuzzy was applied to predict TIs using real genomics data from Saccharomyces cerevisiae. Following one of the latest advances in predicting TIs, constrained probabilistic sparse matrix factorization (cPSMF), and using 19 transcription factors (TFs), we compared AdaFuzzy to four well-known approaches using over-representation analysis and gene set enrichment analysis. AdaFuzzy outperformed these four algorithms. Furthermore, AdaFuzzy was shown to perform comparably to 'ChIP-experimental method' in inferring TIs identified by two sets of large scale ChIP-chip data, respectively. AdaFuzzy was also able to classify all predicted TIs into one or more of the four promoter architectures. The results coincided with known promoter architectures in yeast and provided insights into transcriptional regulatory mechanisms.ConclusionAdaFuzzy successfully integrates multiple types of data (sequence, ChIP, and microarray) to predict transcriptional regulatory networks. The validated success in the prediction results implies that AdaFuzzy can be applied to uncover TIs in yeast.

Dataset Information

A Hybrid MCDM Approach Based on Fuzzy-Logic and DEMATEL to Evaluate Adult Obesity.

Publications

A Hybrid MCDM Approach Based on Fuzzy-Logic and DEMATEL to Evaluate Adult Obesity.

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