Targeting the immune microenvironment in mantle cell lymphoma: implications for current and emerging therapies.
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ABSTRACT:
SUBMITTER: Qualls D
PROVIDER: S-EPMC9741766 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Publications
Targeting the immune microenvironment in mantle cell lymphoma: implications for current and emerging therapies.
Qualls David D Kumar Anita A Epstein-Peterson Zachary D ZD
Leukemia & lymphoma 20220615 11
Mantle cell lymphoma (MCL) is a morphologically and phenotypically heterogeneous subtype of non-Hodgkin lymphoma, and has historically been associated with poor outcomes. However, recent advances in our understanding of this disease have yielded new targeted and immune-based therapies with promising activity. Immune-based therapies such as monoclonal antibodies, immunomodulators, and CAR T cells have significantly improved outcomes and are now standard of care in MCL. In this review, we describe ...[more]
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