Synthetic CT in Musculoskeletal Disorders: A Systematic Review.
Ontology highlight
ABSTRACT: Abstract
Repeated computed tomography (CT) examinations increase patients' ionizing radiation exposure and health costs, making an alternative method desirable. Cortical and trabecular bone, however, have short T2 relaxation times, causing low signal intensity on conventional magnetic resonance (MR) sequences. Different techniques are available to create a "CT-like" contrast of bone, such as ultrashort echo time, zero echo time, gradient-echo, and susceptibility-weighted image MR sequences, and artificial intelligence. This systematic review summarizes the essential technical background and developments of ultrashort echo time, zero echo time, gradient-echo, susceptibility-weighted image MR imaging sequences and artificial intelligence; presents studies on research and clinical applications of "CT-like" MR imaging; and describes their main advantages and limitations. We also discuss future opportunities in research, which patients would benefit the most, the most appropriate situations for using the technique, and the potential to replace CT in the clinical workflow.
SUBMITTER: Lombardi AF
PROVIDER: S-EPMC9742139 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Publications
Synthetic CT in Musculoskeletal Disorders: A Systematic Review.
Lombardi Alecio F AF Ma Ya-Jun YJ Jang Hyungseok H Jerban Saeed S Du Jiang J Chang Eric Y EY Chung Christine B CB
Investigative radiology 20220829 1
<h4>Abstract</h4>Repeated computed tomography (CT) examinations increase patients' ionizing radiation exposure and health costs, making an alternative method desirable. Cortical and trabecular bone, however, have short T2 relaxation times, causing low signal intensity on conventional magnetic resonance (MR) sequences. Different techniques are available to create a "CT-like" contrast of bone, such as ultrashort echo time, zero echo time, gradient-echo, and susceptibility-weighted image MR sequenc ...[more]
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