In vivo-induced genes in Pseudomonas aeruginosa.
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ABSTRACT:
SUBMITTER: Handfield M
PROVIDER: S-EPMC97428 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Publications
In vivo-induced genes in Pseudomonas aeruginosa.
Handfield M M Lehoux D E DE Sanschagrin F F Mahan M J MJ Woods D E DE Levesque R C RC
Infection and immunity 20000401 4
In vivo expression technology was used for testing Pseudomonas aeruginosa in the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity to known virulence factors involved in iron acquisition via an open reading frame (called pvdI) implicated in pyoverdine biosynthesis, membrane biogenesis (FtsY), and adhesion (Hag2). ...[more]
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