Recombinant Staphylococcus aureus exfoliative toxins are not bacterial superantigens.
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ABSTRACT:
SUBMITTER: Plano LR
PROVIDER: S-EPMC97528 | biostudies-literature | 2000 May
REPOSITORIES: biostudies-literature
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Recombinant Staphylococcus aureus exfoliative toxins are not bacterial superantigens.
Plano L R LR Gutman D M DM Woischnik M M Collins C M CM
Infection and immunity 20000501 5
Staphylococcal scalded-skin syndrome is an exfoliative dermatitis characterized by the separation of the epidermis at the stratum granulosum. This disruption is mediated by one of two Staphylococcus aureus exotoxins, exfoliative toxins A and B (ETA and ETB). Both ETA and ETB have been reported to be bacterial superantigens. A controversy exists, however, as other data indicate that these exotoxins are not superantigens. Here we demonstrate that recombinant exfoliative toxins produced in Escheric ...[more]
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