Ontology highlight
ABSTRACT:
SUBMITTER: Gilis-Januszewska A
PROVIDER: S-EPMC9755355 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Gilis-Januszewska Aleksandra A Bogusławska Anna A Rzepka Ewelina E Ziaja Witold W Hubalewska-Dydejczyk Alicja A
Frontiers in endocrinology 20221202
Cushing disease (CD) is caused by a pituitary tumor which oversecretes adrenocorticotropic hormone (ACTH). It is a serious endocrine disease associated with increased mortality and impaired quality of life. The management of CD remains challenging. Although transsphenoidal surgery is the treatment of choice in most cases, in approximately half of CD patients, second or third-line treatment options are needed. Currently, new medical therapies are available which target adrenal steroidogenesis, pi ...[more]