Protocol to analyze population structure and migration history based on human genome variation data.
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ABSTRACT:
SUBMITTER: Zhao Z
PROVIDER: S-EPMC9758492 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Publications
Protocol to analyze population structure and migration history based on human genome variation data.
Zhao Zicheng Z Wang Yinan Y Zhang Zhe Z Li Shuai Cheng SC
STAR protocols 20221213 1
We describe a protocol to integrate genome variation data from different datasets and explore the population structure and migration history of human populations. This protocol provides semi-automated scripts to perform and visualize the effect of variant filtering strategy on eliminating batch effects, principal component analysis, ancestry component analysis, historical population effective size inference, and migration and isolation analysis based on independent biallelic SNPs, genotype likel ...[more]
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