Ontology highlight
ABSTRACT:
SUBMITTER: Jia L
PROVIDER: S-EPMC9773193 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Jia Lin L Chen Naifei N Chen Xiao X Niu Chao C Liu Ziling Z Ma Kewei K Wang Nanya N Yang Lei L Zhao Yuguang Y Song Wei W Lu Jin J Chen Chen C Cong Xiaofeng X Wang Xu X Xu Yinghui Y Cui Guozhen G Liu Zengguang Z Chen Rongrong R Li Wei W Cui Jiuwei J
Frontiers in immunology 20221208
This pilot study (NCT03958097; https://www.clinicaltrials.gov/ct2/show/NCT03958097) was aimed to evaluate the efficacy and safety of PD-1 antibody combined autologous NK cells in the treatment of patients with stage IIIB/IIIC or IV non-small-cell lung cancer (NSCLC) who failed the first-line platinum-based chemotherapy. All patients received both sintilimab 200mg and 3×10<sup>9</sup> NK cells every 3 weeks. 20 patients were enrolled, median follow up time was 22.6 months. The median PFS was 11.6 ...[more]