Cathepsins Trigger Cell Death and Regulate Radioresistance in Glioblastoma.
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ABSTRACT:
SUBMITTER: Ding X
PROVIDER: S-EPMC9777369 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
Cathepsins Trigger Cell Death and Regulate Radioresistance in Glioblastoma.
Ding Xiaofeng X Zhang Chen C Chen Huajian H Ren Minghua M Ren Minghua M Liu Xiaodong X
Cells 20221217 24
Treatment of glioblastoma (GBM) remains very challenging, and it is particularly important to find sensitive and specific molecular targets. In this work, we reveal the relationship between the expression of cathepsins and radioresistance in GBM. We analyzed cathepsins (cathepsin B, cathepsin D, cathepsin L, and cathepsin Z/X), which are highly associated with the radioresistance of GBM by regulating different types of cell death. Cathepsins could be potential targets for GBM treatment. ...[more]
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