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Characterization of a Novel Pathogenic Reovirus in Grasshoppers.

ABSTRACT: Grasshoppers can swarm in the millions and destroy crops over wide areas, posing a major economic threat to agriculture. A wide range of insect-related viruses has recently been reported in the metagenomics of grasshoppers. Here, we identified and isolated a novel reovirus from grasshoppers, named Acrididae reovirus (ARV). The complete genome of ARV was composed of nine dsRNA segments. Phylogenetic analysis revealed that ARV formed a monophyletic lineage with unclassified insect-associated reoviruses and was sufficiently distinct from known genera of Reoviridae. ARV could replicate in its host Locusta migratoria and result in host death. Lower-dose ARV infection affected ovary development and resulted in a significant reduction in fecundity. The identification and characterization of a novel pathogenic reovirus could potentially promote the development of new biological control agents.

SUBMITTER: Xu Y

PROVIDER: S-EPMC9783633 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Characterization of a Novel Pathogenic Reovirus in Grasshoppers.

Xu Yao Y Jiang Jingyi J Wang Zhen Z Tian Jingjing J Shi Wangpeng W Cao Chuan C

Viruses 20221216 12

Grasshoppers can swarm in the millions and destroy crops over wide areas, posing a major economic threat to agriculture. A wide range of insect-related viruses has recently been reported in the metagenomics of grasshoppers. Here, we identified and isolated a novel reovirus from grasshoppers, named Acrididae reovirus (ARV). The complete genome of ARV was composed of nine dsRNA segments. Phylogenetic analysis revealed that ARV formed a monophyletic lineage with unclassified insect-associated reovi ...[more]

PMID: 36560814

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