Dataset Information

Iron-deficiency anemia following herpetic esophagitis in a previously healthy female

ABSTRACT:

Introduction

Herpetic Esophagitis is caused by the Herpes Simplex virus, which generally affects immunocompromised individuals and is rarely seen in healthy individuals. Symptoms are usually self-limiting.

Case presentation

We report the case of a 68-year-old female who presented with odynophagia, dysphagia, and epigastric pain with no other underlying disease. Endoscopic findings of soft, nodular, and friable growths just above the squamocolumnar junction with diffuse ulcerations in the distal esophagus, led to the diagnosis. It was confirmed with a histopathological report which revealed multinucleated giant cells with eosinophilic intranuclear inclusions. During follow-up, laboratory investigations revealed iron deficiency anemia, which was the consequence of GI bleeding.

Clinical discussion

Herpes Simplex virus esophagitis can occur in immunocompetent individuals and even it can cause food impaction and GI bleeding, which can lead to Iron deficiency anemia.

Conclusion

Hence, follow-up of patients is important for early diagnosis and intervention of any complications that may arise. Highlights • Herpetic Esophagitis is caused by Herpes Simplex virus, which generally affects immunocompromised individuals but can also affect immunocompetent individuals.• Patients usually present with odynophagia and dysphagia due to mucosal erosion and ulceration in the esophagus.• Diagnosis is usually established with an upper endoscopy and confirmed by a biopsy of the lesion. Acyclovir is highly beneficial for a symptomatic response.• Patients must be assessed timely and follow-up is very crucial. Otherwise, even in immunocompetent patients, complications like GI bleeding resulting in Iron deficiency Anemia may occur. Early intervention with symptomatic management is required for the complications if present.

SUBMITTER: Bhattarai A

PROVIDER: S-EPMC9793130 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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