Ontology highlight
ABSTRACT:
SUBMITTER: Torres-Perez JV
PROVIDER: S-EPMC9793288 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Torres-Pérez Jose V JV Anagianni Sofia S Mech Aleksandra M AM Havelange William W García-González Judit J Fraser Scott E SE Vallortigara Giorgio G Brennan Caroline H CH
iScience 20221201 1
BAZ1B is a ubiquitously expressed nuclear protein with roles in chromatin remodeling, DNA replication and repair, and transcription. Reduced <i>BAZ1B</i> expression disrupts neuronal and neural crest development. Variation in the activity of BAZ1B has been proposed to underly morphological and behavioral aspects of domestication through disruption of neural crest development. Knockdown of <i>baz1b</i> in <i>Xenopus</i> embryos and <i>Baz1b</i> loss-of-function (LoF) in mice leads to craniofacial ...[more]