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Genomic Microevolution of Vibrio cholerae O1, Lake Tanganyika Basin, Africa.


ABSTRACT: Africa's Lake Tanganyika basin is a cholera hotspot. During 2001-2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin.

SUBMITTER: Hounmanou YMG 

PROVIDER: S-EPMC9796204 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Africa's Lake Tanganyika basin is a cholera hotspot. During 2001-2020, Vibrio cholerae O1 isolates obtained from the Democratic Republic of the Congo side of the lake belonged to 2 of the 5 clades of the AFR10 sublineage. One clade became predominant after acquiring a parC mutation that decreased susceptibility to ciprofloxacin. ...[more]

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