Ontology highlight
ABSTRACT:
SUBMITTER: Vardeny O
PROVIDER: S-EPMC9800271 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Vardeny Orly O Fang James C JC Desai Akshay S AS Jhund Pardeep S PS Claggett Brian B Vaduganathan Muthiah M de Boer Rudolf A RA Hernandez Adrian F AF Lam Carolyn S P CSP Inzucchi Silvio E SE Martinez Felipe A FA Kosiborod Mikhail N MN DeMets David D O'Meara Eileen E Zieroth Shelley S Comin-Colet Josep J Drozdz Jaroslaw J Chiang Chern-En CE Kitakaze Masafumi M Petersson Magnus M Lindholm Daniel D Langkilde Anna Maria AM McMurray John J V JJV Solomon Scott D SD
Nature medicine 20221215 12
With modern treatments for heart failure with reduced ejection fraction (EF), indicative of impaired cardiac systolic function, patients may exhibit an increase in EF. Limited data are available regarding the clinical management of this growing population, categorized as heart failure with improved EF (HFimpEF), which has a high event rate and has been excluded from virtually all prior heart failure outcomes trials. In a prespecified analysis of the DELIVER trial ( NCT03619213 ), of a total of 6 ...[more]