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Protocol for making an animal model of "blindsight" in macaque monkeys.


ABSTRACT: Patients with damage to the primary visual cortex (V1) can respond correctly to visual stimuli in their lesion-affected visual field above the chance level, an ability named blindsight. Here, we present a protocol for making an animal model of blindsight in macaque monkeys. We describe the steps to perform pre-lesion training of monkeys on a visual task, followed by lesion surgery, post-lesion training, and evaluation of blindsight. This animal model can be used to investigate the source of visual awareness. For complete details on the use and execution of this protocol, please refer to Yoshida et al. (2008)1 and Takakuwa et al. (2021).2.

SUBMITTER: Takakuwa N 

PROVIDER: S-EPMC9803826 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Protocol for making an animal model of "blindsight" in macaque monkeys.

Takakuwa Norihiro N   Isa Kaoru K   Yamaguchi Reona R   Onoe Hirotaka H   Takahashi Jun J   Yoshida Masatoshi M   Isa Tadashi T  

STAR protocols 20221223 1


Patients with damage to the primary visual cortex (V1) can respond correctly to visual stimuli in their lesion-affected visual field above the chance level, an ability named blindsight. Here, we present a protocol for making an animal model of blindsight in macaque monkeys. We describe the steps to perform pre-lesion training of monkeys on a visual task, followed by lesion surgery, post-lesion training, and evaluation of blindsight. This animal model can be used to investigate the source of visu  ...[more]

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