Ontology highlight
ABSTRACT:
SUBMITTER: Singh PB
PROVIDER: S-EPMC9845736 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Singh Prim B PB Zhakupova Assem A
Development (Cambridge, England) 20221116 22
'Age reprogramming' refers to the process by which the molecular and cellular pathways of a cell that are subject to age-related decline are rejuvenated without passage through an embryonic stage. This process differs from the rejuvenation observed in differentiated derivatives of induced pluripotent stem cells, which involves passage through an embryonic stage and loss of cellular identity. Accordingly, the study of age reprogramming can provide an understanding of how ageing can be reversed wh ...[more]