Vibrio cholerae tolC is required for bile resistance and colonization.
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ABSTRACT:
SUBMITTER: Bina JE
PROVIDER: S-EPMC98549 | biostudies-literature | 2001 Jul
REPOSITORIES: biostudies-literature
Publications
Vibrio cholerae tolC is required for bile resistance and colonization.
Infection and immunity 20010701 7
TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization. ...[more]
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