Intracellular common gardens reveal niche differentiation in transposable element community during bacterial adaptive evolution.

ABSTRACT: The distribution and abundance of transposable elements across the tree of life have significantly shaped the evolution of cellular organisms, but the underlying mechanisms shaping these ecological patterns remain elusive. Here we establish a "common garden" approach to study causal ecological interactions between a xenogeneic conditional lethal sacB gene and the community of transposable insertion sequences (ISs) in a multipartite prokaryote genome. Xenogeneic sacB of low, medium, or high GC content was individually inserted into three replicons of a model bacterium Sinorhizobium fredii, and exhibited replicon- and GC-dependent variation in genetic stability. This variation was largely attributable to multidimensional niche differentiation for IS community members. The transposition effic

SUBMITTER: Guo H 

PROVIDER: S-EPMC9860058 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature