Dataset Information

Emotion regulation in young adults with family history of harmful alcohol use: A fMRI study.

ABSTRACT:

Background

Alcohol use disorder is associated with difficulties in emotion regulation and cognitive reappraisal. Family history of harmful alcohol use increases risk of substance use disorders, but no studies have examined whether family history is associated with altered neural activation during cognitive reappraisal relative to passive viewing of negative images in a sample of young adults without current substance use disorders.

Methods

Participants (N = 75 with positive [n = 31] or negative [n = 44] family histories of harmful alcohol use) completed the emotion regulation task during an MRI scan, and the Emotion Regulation Questionnaire to assess use of emotion regulation and suppression strategies. Whole-brain analyses and amygdala region of interest analyses using linear mixed-effects models assessed family history group and cue effects on neural activation during the task.

Results

The groups did not differ on trait reappraisal, suppression, or negative emotion following reappraisal. In general, group effects in whole-brain and amygdala activation during the cognitive reappraisal contrast indicated small effect sizes (2.2% of voxels had d>0.20) that were not significantly different. Participants with positive family histories engaged the right middle and superior frontal gyri to a greater extent than participants with negative family histories during the decrease-negative cue (t = 4.14, p = .001).

Conclusions

For at-risk young adults without current harmful substance use, family history of harmful alcohol use does not appear to be associated with disrupted emotion regulation when instructed to apply cognitive reappraisal. Reappraisal may be a feasible therapeutic target for those who develop a substance use disorder with associated emotion dysregulation.

SUBMITTER: Kirk-Provencher KT

PROVIDER: S-EPMC9875721 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Publications

Emotion regulation in young adults with family history of harmful alcohol use: A fMRI study.

Kirk-Provencher Katelyn T KT Penner Anne E AE McRae Kateri K Gowin Joshua L JL

Drug and alcohol dependence 20221222

<h4>Background</h4>Alcohol use disorder is associated with difficulties in emotion regulation and cognitive reappraisal. Family history of harmful alcohol use increases risk of substance use disorders, but no studies have examined whether family history is associated with altered neural activation during cognitive reappraisal relative to passive viewing of negative images in a sample of young adults without current substance use disorders.<h4>Methods</h4>Participants (N = 75 with positive [n = 3 ...[more]

PMID: 36610254

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Project description:Objective: Driving while impaired by alcohol or drugs increases the risk of motor vehicle fatalities, the leading cause of death among young adults. The current study documented the prevalence of driving after alcohol and marijuana use in the past 2 weeks as well as the prevalence of riding with a driver who had used each substance during that time frame. We tested whether young adults who lived with family members (i.e., their parents or their children) were less likely to engage in these behaviors. Methods: Participants aged 18-25 who resided in nonmetropolitan areas in the United States (N?=?1,131; 55% female, Mage = 22.6) completed an online survey. Multivariate logistic regressions examined alcohol- and marijuana-related driving and riding behaviors adjusting for demographic factors. Interactions tested whether associations varied by gender. Results: In the 2 weeks prior to the survey, 17% of participants drove after drinking alcohol and 21% had ridden with a driver who had been drinking. The prevalence of driving after marijuana use was 11%, and 16% of the sample had ridden with a driver who had been using marijuana. Participants who lived with their parents were less likely to ride with a driver who had been using alcohol or marijuana (adjusted odds ratios [AORs]?=?0.71 and 0.55, respectively). Living with parents was also associated negatively with driving after both substances, but these associations were no longer significant when controlling for substance use frequency and driving frequency. Surprisingly, the odds of driving after marijuana use were over 2 times larger for young adults who lived with their children. For women, but not men, residing with children decreased the odds of driving and riding after alcohol use. Conclusions: Living with parents protects against riding after substance use among young adults. Prevention programs should target young adults who live independently or those transitioning away from the parental home. Furthermore, given the higher rates of driving after marijuana use among young adult parents, this group should be educated about the risks associated with this behavior.

Dataset Information

Emotion regulation in young adults with family history of harmful alcohol use: A fMRI study.

Background

Methods

Results

Conclusions

Publications

Emotion regulation in young adults with family history of harmful alcohol use: A fMRI study.

Similar Datasets

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