Ontology highlight
ABSTRACT:
SUBMITTER: Dendooven T
PROVIDER: S-EPMC9890229 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Dendooven Tom T Sonnleitner Elisabeth E Bläsi Udo U Luisi Ben F BF
The EMBO journal 20221212 3
The widely occurring bacterial RNA chaperone Hfq is a key factor in the post-transcriptional control of hundreds of genes in Pseudomonas aeruginosa. How this broadly acting protein can contribute to the regulatory requirements of many different genes remains puzzling. Here, we describe cryo-EM structures of higher order assemblies formed by Hfq and its partner protein Crc on control regions of different P. aeruginosa target mRNAs. Our results show that these assemblies have mRNA-specific quatern ...[more]