Dataset Information

Effects of Ageing in Disinfectant Solution on the Corrosion Resistance and Antimicrobial Behavior of Copper Alloys.

ABSTRACT: This work studies two copper-based alloys as potential antimicrobial weapons for sectors where surface hygiene is essential. Effects of different alloying elements addition at the same Cu content (92.5% by weight) on the corrosion resistance and the antibacterial performance of two copper alloys were studied in an aerated disinfectant solution (0.25% v/v Aniosurf Premium (D)) by electrochemical corrosion, X-ray photoelectron spectroscopy (XPS), time-of-flight secondary ion mass spectroscopy (ToF-SIMS) and antibacterial tests. Results showed that the nature of the alloying elements had a clear influence on the corrosion resistance and antibacterial performance. Electrochemical impedance results and surface analyses demonstrate the presence of organic compounds bound on the substrate and that a film covers part of the total active surface and may act as a protective barrier by preventing the interaction between metal and solution, decreasing the antimicrobial performance of copper-based materials. Low zinc and silicon contents in copper alloys allows for better aging behavior in D solution while maintaining good antibacterial performance. The XPS and ToF-SIMS results indicated that artificial aging in disinfectant enhanced Cu enrichment in the organic film formed, which could effectively stimulate the release of Cu ions from the surface.

SUBMITTER: Lazar FS

PROVIDER: S-EPMC9921941 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Effects of Ageing in Disinfectant Solution on the Corrosion Resistance and Antimicrobial Behavior of Copper Alloys.

Lazar Florica Simescu FS Colin Marius M Carré Gaëlle G Bachelard Nicolas N Chopart Jean-Paul JP Gangloff Sophie C SC

Molecules (Basel, Switzerland) 20230118 3

This work studies two copper-based alloys as potential antimicrobial weapons for sectors where surface hygiene is essential. Effects of different alloying elements addition at the same Cu content (92.5% by weight) on the corrosion resistance and the antibacterial performance of two copper alloys were studied in an aerated disinfectant solution (0.25% <i>v/v</i> Aniosurf Premium (D)) by electrochemical corrosion, X-ray photoelectron spectroscopy (XPS), time-of-flight secondary ion mass spectrosco ...[more]

PMID: 36770646

Similar Datasets

Project description:IntroductionChemical disinfection is state of the art in preventing spread of infectious agents in the healthcare setting. Additionally, the antimicrobial properties of solid copper alloy surfaces against various microorganisms have recently been substantiated. Thus, antimicrobially active copper surfaces may serve as an additional barrier against distribution of pathogenic microorganisms and be combined with chemical disinfection measures in the hospital. The aim of this study was therefore to investigate on a quantitative basis whether the combination of chemical disinfectants with copper alloy surfaces results in an overall compromised, combined or even synergistic antimicrobial efficacy.MethodsExperiments were carried out using the quantitative carrier test devised by the German Society for Hygiene and Microbiology (DGHM) to study antimicrobial efficacy of chemical disinfectants. Requirements for microbicidal efficacy as defined by prEN 14885 were applied. The chemical disinfectants tested in our study contained alcohols (ethanol, 1-propanol), quaternary ammonium compounds (benzalkonium chloride) and glutaraldehyde as actives. Quantitative carrier tests were carried out on different carriers (tiles, copper alloy discs, stainless steel discs) using Pseudomonas aeruginosa, Staphylococcus aureus, Kocuria rhizophila and Candida albicans as test organisms.ResultsFor the alcohol-based disinfectant no difference in antimicrobial efficacy was observed when applied to antimicrobial active copper alloy carriers, tiles or stainless steel discs. For all test organisms microbial contamination was reduced to the detection limit of < 1 log (CFU/ml) within a contact time of 2 min indicating a ≥ 5 log reduction for the tested bacteria and a ≥ 4 log reduction for the yeast, as being requested for chemical disinfectants by prEN 14885. In order to elucidate a potential synergism the chemical disinfectant based on quaternary ammonium compounds (benzalkonium chloride) and glutaraldehyde was used at a sub-effective concentration. Hence, no complete reduction of microbial contamination was achieved on stainless steel or tile carriers for Pseudomonas aeruginosa and Candida albicans. Interestingly, when using copper alloy carriers complete reduction indicating a ≥ 5 log reduction for P. aeruginosa and a ≥ 4 log reduction for C. albicans was detected. Thus, data of this study indicates that solid copper alloy surfaces and disinfectants synergize.ConclusionsAccording to this data, commercially available disinfectants based on alcohol, quaternary ammonium compounds and aldehyde can effectively be combined in a dual strategy with solid copper alloy surfaces to reduce microbial contamination.

Project description:Magnesium-based alloys are the most widely used materials for degradable metallic implants and have considerable potential for bone applications owing to their excellent stimulating effect on osteogenesis. However, their high corrosion rate limits their structural stability and causes oxygen deficiency and an excessive increase in the pH around the defect area during bone healing. Magnesium oxides, which are the main corrosion products of Mg, are nontoxic materials with useful effects on new bone formation and pH neutralization. Metal-phenolic networks were introduced recently as a cost-effective and efficient surface modifier and were fabricated by deposition of nanosized metal oxides on different types of substrates using the chemical reaction between phenolic groups and metallic ions. In this study, magnesium oxide films were formed successfully on a Mg-based substrate using Mg-phenolic networks. The effects of various coating parameters on the surface morphology, corrosion resistance, degradation behavior, wettability, and osteocompatibility of degradable metallic materials after surface modification with Mg-phenolic networks were thoroughly investigated for the first time. The results showed that the initial concentration of Mg ions was the main parameter affecting the corrosion resistance, which was almost as much as 3 times that of uncoated samples. Additionally, cytotoxicity and viability assessment and observation of the morphological changes in bonelike cells showed that the in vitro osteocompatibility was significantly enhanced by coatings with Mg concentrations of 2.4-3.6 mg mL-1. Finally, in vivo animal studies using the rat calvarial defect model confirmed that the proposed coating method mitigated the formation of gas cavities around the implantation area by reducing the corrosion rate of the Mg-based implant. The nanosized metal oxides produced by the Mg-phenolic network significantly improved the biodegradability and osteocompatibility of Mg alloys, suggesting a potential approach to advancing the clinical application of Mg alloys.

Dataset Information

Effects of Ageing in Disinfectant Solution on the Corrosion Resistance and Antimicrobial Behavior of Copper Alloys.

Publications

Effects of Ageing in Disinfectant Solution on the Corrosion Resistance and Antimicrobial Behavior of Copper Alloys.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets