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Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells.

ABSTRACT: Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were "cartilage", "temporomandibular joint", "mesenchymal stem cells", and "osteoarthritis". Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required.

SUBMITTER: da Silva ZA

PROVIDER: S-EPMC9965396 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells.

da Silva Zuleni Alexandre ZA Melo Wallacy Watson Pereira WWP Ferreira Hadassa Helez Neves HHN Lima Rafael Rodrigues RR Souza-Rodrigues Renata Duarte RD

Journal of functional biomaterials 20230213 2

Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive sea ...[more]

PMID: 36826902

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Dataset Information

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells.

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Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells.

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