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Cost-Effective Droplet Generator for Portable Bio-Applications.

ABSTRACT: The convenient division of aqueous samples into droplets is necessary for many biochemical and medical analysis applications. In this article, we propose the design of a cost-effective droplet generator for potential bio-chemical application, featuring two symmetric tubes. The new droplet generator revisits the relationship between capillary components and liquid flow rates. The size of generated droplets by prototype depends only on generator dimensions, without precisely needing to control external flow conditions or driving pressure, even when the relative extreme difference in flow rate for generating nL level droplets is over 57.79%, and the relative standard deviation (RSD) of the volume of droplets is barely about 9.80%. A dropper working as a pressure resource is used to verify the rapidity and robustness of this principle of droplet generation, which shows great potential for a wide range of droplet-based applications.

SUBMITTER: Du L

PROVIDER: S-EPMC9966110 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Cost-Effective Droplet Generator for Portable Bio-Applications.

Du Lin L Li Yuxin Y Wang Jie J Zhou Zijian Z Lan Tian T Jing Dalei D Wu Wenming W Zhou Jia J

Micromachines 20230217 2

The convenient division of aqueous samples into droplets is necessary for many biochemical and medical analysis applications. In this article, we propose the design of a cost-effective droplet generator for potential bio-chemical application, featuring two symmetric tubes. The new droplet generator revisits the relationship between capillary components and liquid flow rates. The size of generated droplets by prototype depends only on generator dimensions, without precisely needing to control ext ...[more]

PMID: 36838166

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