Ontology highlight
ABSTRACT:
SUBMITTER: Wu ZY
PROVIDER: S-EPMC9969067 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Wu Zong-Yen ZY Sun Wan W Shen Yihui Y Pratas Jimmy J Suthers Patrick F PF Hsieh Ping-Hung PH Dwaraknath Sudharsan S Rabinowitz Joshua D JD Maranas Costas D CD Shao Zengyi Z Yoshikuni Yasuo Y
Metabolic engineering communications 20230216
Methyl methacrylate (MMA) is an important petrochemical with many applications. However, its manufacture has a large environmental footprint. Combined biological and chemical synthesis (semisynthesis) may be a promising alternative to reduce both cost and environmental impact, but strains that can produce the MMA precursor (citramalate) at low pH are required. A non-conventional yeast, <i>Issatchenkia orientalis</i>, may prove ideal, as it can survive extremely low pH. Here, we demonstrate the e ...[more]