Ontology highlight
ABSTRACT:
SUBMITTER: Poyatos L
PROVIDER: S-EPMC9981643 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Poyatos Lourdes L Pérez-Mañá Clara C Hladun Olga O Núñez-Montero Melani M de la Rosa Georgina G Martín Soraya S Barriocanal Ana Maria AM Carabias Lydia L Kelmendi Benjamin B Taoussi Omayema O Busardò Francesco Paolo FP Fonseca Francina F Torrens Marta M Pichini Simona S Farré Magí M Papaseit Esther E
Frontiers in pharmacology 20230217
Methylone is one of the most common synthetic cathinones popularized as a substitute for 3,4-methylenedioxymethamphetamine (MDMA, midomafetamine) owing to its similar effects among users. Both psychostimulants exhibit similar chemistry (i.e., methylone is a β-keto analog of MDMA) and mechanisms of action. Currently, the pharmacology of methylone remains scarcely explored in humans. Herein, we aimed to evaluate the acute pharmacological effects of methylone and its abuse potential in humans when ...[more]