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Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis.
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ABSTRACT: Introduction and importance
Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2-10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities.Case presentation
In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position.Clinical discussion
The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves.Conclusion
This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach.
SUBMITTER: Komarov RN
PROVIDER: S-EPMC9988661 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis.
International journal of surgery case reports 20230201
<h4>Introduction and importance</h4>Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2-10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities.<h4>Case presentation</h4>In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic val ...[more]