Ontology highlight
ABSTRACT:
SUBMITTER: Radostin Danev
PROVIDER: EMPIAR-10216 | biostudies-other |
REPOSITORIES: biostudies-other
Trends in biochemical sciences 20190508 10
Cryo-electron microscopy (cryo-EM) has emerged as a powerful structure determination technique. Its most prolific branch is single particle analysis (SPA), a method being used in a growing number of laboratories worldwide to determine high-resolution protein structures. Cryo-electron tomography (cryo-ET) is another powerful approach that enables visualization of protein complexes in their native cellular environment. Despite the wide-ranging success of cryo-EM, there are many methodological aspe ...[more]