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Cryo-EM structure of mouse heavy-chain apoferritin at 1.62 A


ABSTRACT:

SUBMITTER: Radostin Danev 

PROVIDER: EMPIAR-10216 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Cryo-Electron Microscopy Methodology: Current Aspects and Future Directions.

Danev Radostin R   Yanagisawa Haruaki H   Kikkawa Masahide M  

Trends in biochemical sciences 20190508 10


Cryo-electron microscopy (cryo-EM) has emerged as a powerful structure determination technique. Its most prolific branch is single particle analysis (SPA), a method being used in a growing number of laboratories worldwide to determine high-resolution protein structures. Cryo-electron tomography (cryo-ET) is another powerful approach that enables visualization of protein complexes in their native cellular environment. Despite the wide-ranging success of cryo-EM, there are many methodological aspe  ...[more]

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