Dataset Information
Raw FIB SEM images of a parasitophorous vacuole containing Toxoplasma gondii ?CAP parasites.
Ontology highlight
ABSTRACT:
SUBMITTER: Moritz Treeck
PROVIDER: EMPIAR-10326 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of <i>Toxoplasma gondii</i>.
eLife 20191002
<i>Toxoplasma gondii</i> contains a limited subset of actin binding proteins. Here we show that the putative actin regulator cyclase-associated protein (CAP) is present in two different isoforms and its deletion leads to significant defects in some but not all actin dependent processes. We observe defects in cell-cell communication, daughter cell orientation and the juxtanuclear accumulation of actin, but only modest defects in synchronicity of division and no defect in the replication of the ap ...[more]