Dataset Information
TEM tomograms of Drosophila tracheal terminal cells during subcellular tube formation
Ontology highlight
ABSTRACT:
SUBMITTER: Maria Leptin
PROVIDER: EMPIAR-10434 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Transcytosis via the late endocytic pathway as a cell morphogenetic mechanism.
The EMBO journal 20200713 16
Plasma membranes fulfil many physiological functions. In polarized cells, different membrane compartments take on specialized roles, each being allocated correct amounts of membrane. The Drosophila tracheal system, an established tubulogenesis model, contains branched terminal cells with subcellular tubes formed by apical plasma membrane invagination. We show that apical endocytosis and late endosome-mediated trafficking are required for membrane allocation to the apical and basal membrane domai ...[more]