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Single particle cryo-EM dataset of human adenovirus HAdV-D26

ABSTRACT:

SUBMITTER: Juha T Huiskonen

PROVIDER: EMPIAR-10455 | biostudies-other |

REPOSITORIES: biostudies-other

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Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data.

Abrishami Vahid V Ilca Serban L SL Gomez-Blanco Josue J Rissanen Ilona I de la Rosa-Trevín José Miguel JM Reddy Vijay S VS Carazo José-Maria JM Huiskonen Juha T JT

Progress in biophysics and molecular biology 20200526

Technological advances in transmission electron microscopes and detectors have turned cryogenic electron microscopy (cryo-EM) into an essential tool for structural biology. A commonly used cryo-EM data analysis method, single particle analysis, averages hundreds of thousands of low-dose images of individual macromolecular complexes to determine a density map of the complex. The presence of symmetry in the complex is beneficial since each projection image can be assigned to multiple views of the ...[more]

PMID: 32470354

Publication: 1/2

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