Dataset Information
SBF SEM images of a Zebrafish hindbrain macrophage containing 2 Toxoplasma gondii tachizoites
Ontology highlight
ABSTRACT:
SUBMITTER: Marie-Charlotte Domart
PROVIDER: EMPIAR-10461 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
The zebrafish as a novel model for the <i>in vivo</i> study of <i>Toxoplasma gondii</i> replication and interaction with macrophages.
Disease models & mechanisms 20200720 7
<i>Toxoplasma gondii</i> is an obligate intracellular parasite capable of invading any nucleated cell. Three main clonal lineages (type I, II, III) exist and murine models have driven the understanding of general and strain-specific immune mechanisms underlying <i>Toxoplasma</i> infection. However, murine models are limited for studying parasite-leukocyte interactions <i>in vivo</i>, and discrepancies exist between cellular immune responses observed in mouse versus human cells. Here, we develope ...[more]