Dataset Information
Saccharomyces cerevisiae fatty acid synthase complex
Ontology highlight
ABSTRACT:
SUBMITTER: Holger Stark
PROVIDER: EMPIAR-10470 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell 20200310 6
Fatty acid synthases (FASs) are central to metabolism but are also of biotechnological interest for the production of fine chemicals and biofuels from renewable resources. During fatty acid synthesis, the growing fatty acid chain is thought to be shuttled by the dynamic acyl carrier protein domain to several enzyme active sites. Here, we report the discovery of a γ subunit of the 2.6 megadalton α<sub>6</sub>-β<sub>6</sub>S. cerevisiae FAS, which is shown by high-resolution structures to stabiliz ...[more]